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Dextromethorphan

What is dextromethorphan?

Dextromethorphan (brand names Delsym®, Robitussin®, Balminil®, Benylin ® and many others) is a medication used to treat compulsive behavior. It can also be used as a cough suppressant, although other cough suppressants are typically more effective in cats and dogs.

Its use in cats, dogs, and horses to treat compulsive behavior or cough is “off label” or “extra label”. Many drugs are commonly prescribed for off-label use in veterinary medicine. In these instances, follow your veterinarian’s directions and cautions carefully, as they may be significantly different from those on the label.

How is dextromethorphan given?

This medication will take effect quickly, in about 1 to 2 hours, and improvement in clinical signs should follow.

What if I miss giving my pet the medication?

If you miss a dose, give it as soon as you remember, and then continue with the regular dosing schedule. If it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not give the pet two doses at once.

Are there any potential side effects?

Side effects are uncommon, but may include:

More serious side effects include:

This short-acting medication should stop working within 24 hours, although effects can be longer in pets with liver or kidney disease.

Are there any risk factors for this medication?

Dextromethorphan should NOT BE USED in pets that are allergic to it.

Dextromethorphan should be USED WITH CAUTION in pets that:

Are there any drug interactions I should be aware of?

The following medications should be used with caution when given with dextromethorphan:

Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking.

Is any monitoring needed with this medication?

How do I store dextromethorphan?

Store at room temperature between 68°F and 77°F (20°C and 25°C), protected from moisture.

What should I do in case of emergency?

If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility.

© Copyright 2025 LifeLearn Inc. Used and/or modified with permission under license. This content written by LifeLearn Animal Health (LifeLearn Inc.) is licensed to this practice for the personal use of our clients. Any copying, printing or further distribution is prohibited without the express written consent of LifeLearn. This content does not contain all available information for any referenced medications and has not been reviewed by the FDA Center for Veterinary Medicine, or Health Canada Veterinary Drugs Directorate. This content may help answer commonly asked questions, but is not a substitute for medical advice, or a proper consultation and/or clinical examination of your pet by a veterinarian. Please contact your veterinarian if you have any questions or concerns about your pet’s health. Last updated on Aug 6, 2024.

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